Gorgonia ventalina contains secondary metabolites and calcified sclerites that act as anti-predator defenses. These anti-predator defenses act as successful feeding deterrents to the Cyphoma gibbosum, a common predator of the G. ventalina. Cyphoma gibbosum feeds on gorgonian polyps by crawling slowly over the skeleton. Trotonia hamnerorum is a specialized predator on G. ventalina.
- flamingo tongues (Cyphoma gibbosum)
- nudibranchs (Trotonia hamnerorum)