Unlike Mortierella aplina, Mortierella antarctica is not able to inhibit the bacterial growth of organisms Candida albicans, Escherichia coli, Mycobacterium phlei, Proteus mirabilis, or Staphylococcus aureus (Ding et al., 2016). In the same study, M. antarctica was found to have a cytotoxicity percentage of 44.3/18.6; this rating was measured by the inhibition rate of a lymphocytic leukemic cell line, P388. Ding et al. rated this particular fungus as a ‘medium’ cytotoxin producer in their study (Ding et al., 2016) due to partial inhibition. They conclude that M. antarctica does produce inhibitory compounds, but not at a commercially viable level.
- Ding, Z., L. Li, Q. Che, L. Dehai, G. Qianqun, and Z. Tianjiao. 2016. Richness and bioactivity of culturable soil fungi from the Fildes Peninsula, Antarctic. Extremophiles 20: 425-435 doi:10.1007/s00792-016-0833-y
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