Powassan virus

Il virus di Powassan (POWV) è un arbovirus della famiglia Flaviviridae, genere Flavivirus, appartiene al IV gruppo dei virus a ((+) ssRNA). La specie Powassan virus comprende sia tale virus omonimo che il virus della zecca di cervo.^{[1] [2]}

Il virus POWV ha come vettore le zecche dei generi: Ixodes spp, Dermacentor spp, Haemaphysalis spp. Animali ospiti sono i piccoli mammiferi, ed è diffuso in Russia, USA, Canada.^[3]

Il virus fa parte dei Flavivirus patogeni per l'uomo, è, infatti, causa di encefalite nell'uomo.^[3]

Note

Bibliografia

Testi

• Pei-Yong Shi, Molecular Virology and Control of Flaviviruses, Horizon Scientific Press, 1º gennaio 2012, ISBN 978-1-904455-92-9.
• Paul Shapshak, John T. Sinnott, Charurut Somboonwit and Jens Kuhn, Global Virology I - Identifying and Investigating Viral Diseases, Springer, 13 luglio 2015, pp. 487–, ISBN 978-1-4939-2410-3.
• Richard A. Kaslow, Lawrence R. Stanberry and James W. Le Duc, Viral Infections of Humans: Epidemiology and Control, Springer, 27 settembre 2014, pp. 405–, ISBN 978-1-4899-7448-8.
• Dongyou Liu, Molecular Detection of Human Viral Pathogens, CRC Press, 23 novembre 2010, pp. 314–, ISBN 978-1-4398-1237-2.
• Flavivirus Infections—Advances in Research and Treatment: 2012 Edition: ScholarlyBrief, ScholarlyEditions, 26 dicembre 2012, pp. 6–, ISBN 978-1-4816-1346-0.
• Walter R Schlesinge, The Togaviruses: bio,struc,replication, Elsevier, 2 dicembre 2012, pp. 675–, ISBN 978-0-323-13826-0.
• and Subhash Vasudevan Duane J. Gubler, Eng Eong Ooi, Jeremy Farrar, Dengue and Dengue Hemorrhagic Fever, 2nd Edition, CABI, 29 agosto 2014, pp. 322–, ISBN 978-1-84593-964-9.
• Arbovirus Encephalitis—Advances in Research and Treatment: 2013 Edition: ScholarlyBrief, ScholarlyEditions, 21 giugno 2013, pp. 46–, ISBN 978-1-4816-8522-1.
• Japanese Encephalitis: New Insights for the Healthcare Professional: 2013 Edition: ScholarlyPaper, ScholarlyEditions, 22 luglio 2013, pp. 26–, ISBN 978-1-4816-5982-6.
• Michael W. Scheld, Christina M. Marra and Richard J. Whitley, Infections of the Central Nervous System, Lippincott Williams & Wilkins, 2014, pp. 210–, ISBN 978-1-4511-7372-7.
• Charles H. Calisher & Diane E. Griffin, Emergence and Control of Zoonotic Viral Encephalitides, Springer Science & Business Media, 23 marzo 2004, pp. 191–, ISBN 978-3-211-20454-2.
• Erik De Clercq, Earl R. Kern, Handbook of Viral Bioterrorism and Biodefense, Elsevier, 2003, pp. 129–, ISBN 978-0-444-51326-7.
• Richard V. Goering, Cedric A. Mims, Hazel Dockrell & Mark Zuckerman, Ivan M. Roitt, Peter L. Chiodini, Mims' Medical Microbiology,With STUDENT CONSULT Online Access ,5: Mims' Medical Microbiology, Elsevier Health Sciences, 2013, pp. 370–, ISBN 0-7234-3601-0.
• Debra C. Sellon & Maureen Long, Equine Infectious Diseases, Elsevier Health Sciences, 8 dicembre 2006, pp. 198–, ISBN 1-4377-1061-1.
• Karl Maramorosch & Frederick A. Murphy, Advances in Virus Research, Elsevier Science, 18 aprile 2014, ISBN 978-0-12-800400-5.

Riviste

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• Klema VJ, Padmanabhan R, Choi KH, Flaviviral Replication Complex: Coordination between RNA Synthesis and 51-RNA Capping, in Viruses, vol. 7, n. 8, 2015, pp. 4640-56, DOI:10.3390/v7082837, PMC 4576198, PMID 26287232.
• Jeffries CL, Walker T, The Potential Use of Wolbachia-Based Mosquito Biocontrol Strategies for Japanese Encephalitis, in PLoS Negl Trop Dis, vol. 9, n. 6, 2015, pp. e0003576, DOI:10.1371/journal.pntd.0003576, PMC 4472807, PMID 26086337.
• Wu J, Liu W, Gong P, A Structural Overview of RNA-Dependent RNA Polymerases from the Flaviviridae Family, in Int J Mol Sci, vol. 16, n. 6, 2015, pp. 12943-57, DOI:10.3390/ijms160612943, PMC 4490480, PMID 26062131.
• Blitvich BJ, Firth AE, Insect-specific flaviviruses: a systematic review of their discovery, host range, mode of transmission, superinfection exclusion potential and genomic organization, in Viruses, vol. 7, n. 4, 2015, pp. 1927-59, DOI:10.3390/v7041927, PMC 4411683, PMID 25866904.
• Mezochow AK, Henry R, Blumberg EA, Kotton CN, Transfusion transmitted infections in solid organ transplantation, in Am. J. Transplant., vol. 15, n. 2, 2015, pp. 547-54, DOI:10.1111/ajt.13006, PMID 25612502.
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• Bollati M, Alvarez K, Assenberg R, Baronti C, Canard B, Cook S, Coutard B, Decroly E, de Lamballerie X, Gould EA, Grard G, Grimes JM, Hilgenfeld R, Jansson AM, Malet H, Mancini EJ, Mastrangelo E, Mattevi A, Milani M, Moureau G, Neyts J, Owens RJ, Ren J, Selisko B, Speroni S, Steuber H, Stuart DI, Unge T, Bolognesi M, Structure and functionality in flavivirus NS-proteins: perspectives for drug design, in Antiviral Res., vol. 87, n. 2, 2010, pp. 125-48, DOI:10.1016/j.antiviral.2009.11.009, PMC 3918146, PMID 19945487.
• Wu J, Bera AK, Kuhn RJ, Smith JL, Structure of the Flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing, in J. Virol., vol. 79, n. 16, 2005, pp. 10268-77, DOI:10.1128/JVI.79.16.10268-10277.2005, PMC 1182653, PMID 16051820.
• Kuno G, Chang GJ, Tsuchiya KR, Karabatsos N, Cropp CB, Phylogeny of the genus Flavivirus, in J. Virol., vol. 72, n. 1, 1998, pp. 73-83, PMC 109351, PMID 9420202.
• Zanotto PM, Ernest A. Gould, George F. Gao, Paul H. Harvey e Edward C. Holmes, Population dynamics of flaviviruses revealed by molecular phylogenies, in Proc Natl Acad Sci U S A., vol. 93, n. 2, Jan 1996, pp. 548-53, Bibcode:1996PNAS...93..548Z, DOI:10.1073/pnas.93.2.548, PMC 40088, PMID 8570593.
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